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Robert Woods, Ph.D.

Professor

Biochemistry and Molecular Biology

University of Georgia, Athens, GA 30602

Office: CCRC, Rm 220   
Voice: 706-542-4454
: rwoods@ccrc.uga.edu

Education

Ph.D. Computational & Carbohydrate Chemistry , Queen's University, Canada 1990

B.Sc. Engineering Chemistry, Queen's University, Canada 1985

Research Interests

Carbohydrate-Protein Interactions

Research in the Woods group examines the relationship between carbohydrate structure and biological recognition. Areas of particular interest include carbohydrate recognition as a mechanism for pathogen adhesion and infection; characterizing carbohydrate antigenicity in immunological events; and the development of carbohydrate-specific reagents for the detection of carbohydrate-related disease markers. The research combines advanced computational 3D structure simulations
with experimental methods, such as molecular biology, surface plasmon resonance, flow cytometry, and NMR spectroscopy.

Of Note

Post-doctoral Experience
1990-1991 Postdoctoral Fellow, Laboratory for Molecular Modeling, The University of North Carolina
1991-1994 Postdoctoral Fellow, Glycobiology Institute, The University of Oxford, United Kingdom
Honors and Awards
1985-1986 Queen's University Graduate Fellowship
1986-1987 Province of Ontario Graduate Studies Scholarship
1987-1990 National Sciences and Engineering Research Council of Canada,
NSERC Graduate Scholarship
1990-1992 Natural Sciences and Engineering Research Council of Canada,
NSERC Postdoctoral Fellowship
1992 University of Oxford, Lockey Bequest
1999 Member of Group Study Exchange Program to Argentina, Athens West Rotary Club

Selected Publications

Yongye, A.B., J. Gonzalez-Outeriño, J. Glushka, V. Schutlheis, and R.J. Woods. 2008. The Conformational Properties of Methyl a-(2,8)- di/trisialoside. Implications for anti-Neisseria meningitidis Vaccine Design. Biochemistry 47, 12493–12514.

Fadda, E. and R.J. Woods. 2010. Molecular Simulations of Carbohydrates and Protein-carbohydrate Interactions: Motivation, Issues and Prospects. Drug Disc. Today 15, 596-609.

Kadirvelraj, R., O. Grant, I.J. Goldstein, H.C. Winter, H. Tateno, E. Fadda, and R.J. Woods. 2011. Structure and Binding Analysis of Polyporus squamosus Lectin in Complex with the Neu5Acα2-6Galβ1-4GlcNAc Human-type Influenza Receptor. Glycobiology, 21(7), 973-984.

Fadda, E. and R. J. Woods. 2011. On the role of water models in quantifying the standard binding free energy of highly conserved water molecules in proteins: the case of Concanavalin A. J. Comput. Theor. Chem. 7, 3391–3398.

DeMarco, M.L. and R.J. Woods. 2011. From Agonist to Antagonist: Structure and Dynamics of Innate Immune Glycoprotein MD-2 upon Recognition of Variably Acylated Bacterial Endotoxins. Molecular Immunology, 49, 124-133.